71例慢性骨髓炎的菌群特点及治疗效果

Flora characteristics and treatment effects of 71 cases of chronic osteomyelitis

目的探讨71例慢性骨髓炎的菌群特点和治疗效果。方法对71例慢性骨髓炎患者窦道深部渗出物做细菌培养及药敏试验,术中彻底病灶清除,术后全身和局部应用敏感抗菌药物。结果共培养出病原菌96株,金黄色葡萄球菌占22.9%,铜绿假单胞菌检出率20.8%,64例治愈,7例复发,其中5例检出病原菌对抗菌药物均不敏感。结论对慢性骨髓炎的治疗,在彻底病灶清除的基础上,全身和局部同时应用敏感抗菌药物,可取得较好的治疗效果。

OBJECTIVE To investigate the flora characteristics and treatment effects of 71 cases of chronic osteomyelitis.METHODS Exudate in deep sinus was collected for bacterial culture and sensitivity and debridement was performed during the process of surgery,general and local use of sensitive antibiotics were applied after operation.RESULTS A total of 96 strains of pathogens were cultured,including Staphylococcus aureus（22.9%）,Pseudomonas aeruginosa（20.8%）,64 patients were cured,7 cases were recurrence.The pathogens from 5 cases were not sensitive to antibiotics.CONCLUSION Chronic osteomyelitis should be treated on the basis of debridement,meanwhile sensitive antibiotics was used both in vein and local,which can achieve better treatment efficacy.