肝脏功能严重受损患者相关指标检测结果对比分析

Patient with severely impaired liver function test results of comparative analysis of relevant item

目的:探讨r-谷氨酰转肽酶(r-GT)、胆碱酯酶(CHE)、总胆汁酸(TBA)和凝血四项实验室检测对肝功能受损患者治疗、预后的意义。方法:测定52例肝功能严重受损患者血清r-GT、CHE、TBA及血浆中凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原(FIB),与对照组比较。结果:与对照组比较,肝硬化组r-GT、TBA血清含量明显升高PT、APTT、TT时间延长,CHE、FIB血清含量明显下降,差异均有统计学意义(P<0.001)。结论:通过联合检测凝血功能、肝功能可以观察病情,判定肝功能损害程度及预后。

Objective：To investigate r-GT. CHE.TBA and coagulation laboratory testing for patients, curing and prognostic significance. Method：Determined 52 cases of severely impaired liver function with r-GT, CHE, TBA, and PT.APT.TT and FIB, Compared with control group. Result：Liver cirrhosis group has r-GT, TBA significantly higher serum levels ;PT, APTT, TT prolonged, CHE, FIB was significantly decreased serum levels, the differences were statistically significant （P 〈0.001）. Conclusion：The combined detection of coagulation, liver func- tion can observe the patient＇s condition to determine the extent of damage and prognosis of impaired liver function