缺血性心脑血管事件高危因素的中医干预研究

The Intervention Research of Ischemic Cardiovascular Events Risk Factors Treated by Traditional Chinese Medicine

目的近30年,我国人群心脑血管病的发病率和病死率呈现逐年上升趋势,且发病年龄提前。现代医学已进入"强化降脂、降压、降糖"时代,并已经成为新的研究热点。随着大量缺血性心脑血管事件危险因素的发现,对其防治的重点"前移"成为心脑血管疾病防治的重要研究课题之一。本课题旨在探讨缺血性心脑血管事件高危因素的中医证候特点,为早期干预治疗提供依据。方法中老年人群是多重危险因素聚集发生率较高的特定群体,对该人群进行横断面调查问卷研究并进行前瞻性追踪分析,对比分析观察缺血性心脑血管病人群体与健康人群所合并危险因素的数目,症候学特点以及舌象,脉象特点。经多元回归统计分析,得出结论。结果本课题组目前阶段研究结果表明,急性缺血性心脑血管事件发生前"有征可循",中医证候出现相关规律和特点,其发生存在共同的发病病机"风""痰""瘀"。结论对"风""痰""瘀"三要素进行中医早期的综合干预,在辨证治疗基础上及早给予熄风、化痰、活血干预,可望起到"既病防变"的作用。

Objective Nearly 30 years,China＇s population of cardiovascular disease morbidity and mortality rates showed an upward trend year by year,and a earlier age of onset.Modern medicine has entered the ＂intensive lipid-lowering,antihypertensive,hypoglycemic＂ era,and it has become a new study hotspot.With lots of risk factors for ischemic cardiovascular events has been found,the focus on treatment of disease,＂forward＂ into prevention of disease,and it become a important research topic.Methods Design the questionnaire for the elderly population and make a prospective cross-sectional survey study,contrast the ischemic cardiovascular and cerebrovascular disease population with the healthy people,by multiple regression analysis summarized the related risk factors,characteristics and symptoms of tongue,pulse characteristics.Results The results of the current phase of our study show that before it occur,acute ischemic cardiocerebrovascular events have some signs to follow,TCM appear regular pattern and characteristics.Conclusion Its occurrence with a same pathogenesis,＂the wind＂ ＂sputum,＂ ＂stasis＂.Based on these,the dialectical give xifeng,phlegm,blood intervention is expected to play ＂disease prevention＂ role.