期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

神经干细胞概述及治疗视神经损伤的应用进展 被引量：1

下载PDF
导出
摘要 神经干细胞是具有自我更新、多向分化潜能的细胞群,能分化成神经元、星形胶质细胞和少突胶质细胞。随着干细胞研究技术的不断发展,通过体外培养神经干细胞,移植整合入视网膜各层并定向诱导分化为目的细胞,有望重建视神经功能。本文就神经干细胞的来源、特性、分化调控机制及移植治疗视神经损伤的应用研究进行综述。
作者 张晓鹏 程辉
机构地区 山东万杰医学院解剖学教研室
出处 《中国医药指南》 2011年第26期205-207,共3页 Guide of China Medicine
关键词 神经干细胞 移植 视神经损伤
分类号 R774.6 [医药卫生—眼科]
  • 相关文献

参考文献27

  • 1Reynolds BA,Weiss A.Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system[J].Science,1992,255(5052):1707-1709.
  • 2Mckay HA.Vesicovaginal and vesicocutaneous fistulas:transurethral suture cystorrhaphy as a new closure technique.J Urol,1997,158(4):1513-1516.
  • 3Evans MJ,Kaufman MH.Establishment in culture of pluripotentia lcells from mouse embryos[J].Nature,1981,292(5819):154-156.
  • 4Bain G,Kitchens D,Yao M,et al.Embryonic stem cells express neuronal properties in vitro[J].Dev Biol,1995,168(2):342-357.
  • 5Arnhold S,Klein H,Semkova I.Neurally selected embryonic stem cells inclue tumor formation after long-term survial following engraftment into the subretinal space[J].Invest Ophthalmol Vis Sci,2004,45(12):4251-4255.
  • 6Nakayama T,Momoki-Soga T,Yamaguchi K,et al.Efficient produc-tion of neural stem cells and neurons from embryonic stem cells[J].Neuroreport,2004,15(3):487-491.
  • 7Okabe S,Forsberg-Nilsson K,Spiro AC,et al.Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro[J].Mech Dev,1996,59(1):89-102.
  • 8Lois C,Alvarez-Buylla A.Long-distance neuronal migration in the adult mammalian brain[J].Science,1994,264(5162):1145-1148.
  • 9Alvarez-Buylla A,Garcia-Verdugo JM,Tramontin AD.A unified hypothesis on the lineage of neural stem cells[J].Nat Rev Neurosci,2001,2(4):287-293.
  • 10Snyder EY,Daley GQ,Goodell M.Taking stock and planning forthe next decade:realistic prospects for stem cell therapies for the nervous system[J].J Neurosci Res,2004,76(2):157-168.

二级参考文献10

  • 1白大勇,李根林,刘月月.不同时期神经视网膜免疫抗原分子表达特性[J].眼科新进展,2005,25(3):216-218. 被引量：2
  • 2高俊玮,伍军,柳浩然,陈长青,方芳,周向阳,方加胜.胚胎大鼠神经干细胞的体外培养与鉴定[J].中国神经精神疾病杂志,2005,31(5):385-386. 被引量：8
  • 3WATANABE M, TOKITA Y, KATO M, et al. Intravitreal injections of neurotrophic factors and forskolin enhance survival and axonal regeneration of axotomized beta ganglion cells in cat retina [J]. Neuroscience. 2003, 116(3): 733-742.
  • 4TAKANO M, HORIE H, LIJIMA Y, et al. Brain-derived neurotrophic factor enhances neurite regeneration from retinal ganglion ceils in aged human retina in vitro [J]. Exp Eye Res, 2002, 74(2): 319-323.
  • 5LU P, JONES L L, SNYDER EY, et al. Neural stern cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury [J]. Exp Neurol, 2003, 181(2): 115-129.
  • 6CHEN H, WEBER A J. BDNF enhances retinal ganglion cell survival in cats with optic nerve damage [J]. Invest Ophthalmol Vis Sci, 2001, 4215): 966-974.
  • 7RYU J K, KIM J, CHO S J. et al. Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease [J]. Neurobiol Dis. 2004. 16(1): 68-77.
  • 8GAO H, QIAO X, HEFTI F, et al. Elevated mRNA expression of brain-derived neurotrophic factor in retinal ganglion ceil layer after optic nerve injury [J]. Invest Ophthalmol Vis Sci, 1997, 38(9): 1840-1847.
  • 9CHIDLOW G, CASSON R, SOBRADO CALVO P, et al. Measurement of retinal injury in the rat after optic nerve transection: an RT-PCR study [J]. Mol Vis. 2005, 11: 387-396.
  • 10Ola Rauer,Fredrik Ghosh. Survival of full-thickness retinal xenotransplants without immunosuppression[J] 2001,Graefe’s Archive for Clinical and Experimental Ophthalmology(2):145～151

共引文献8

同被引文献23

  • 1柳浩然,杨长虹,高俊玮,薄巍巍,吴海权,伍军,陈风华,方加胜.神经干细胞移植后在视神经损伤大鼠视网膜内表达BDNF的研究[J].中国微侵袭神经外科杂志,2007,12(1):28-30. 被引量：7
  • 2Zhu XH, Jiang B, Zhang P, et al.Effect of human umbilical cord bloodstem cells on flash visual evokedpotential in traumatic optic neuropathyin rats [J]. Cent South Univ(MedSci),2011,36(5):405-410.
  • 3Jiang Y, JaKagirdar BN, ReinhardtRL, et al. Pluripotency of mesenchymalstem cells derived from adult marrow[J]. Nature’2002,418(6893):41.
  • 4Brazelton TR,Rossi FM, Keshet GL,et al. From marrow to brain : expressionof neuronal phenotypes in adult mice[J]. Science,2000(290) :1775.
  • 5Koike-Kiriyama N, Adachi Y,Minamino K, et al. Human cord bloodcells can differentiate into retinal nervecells [J].Acta Neurobiol Exp,2007,67(4):359-365.
  • 6Isabel Zwart, Andrew J Hill, Faisal Al-Allaf, et al. Umbilical cord bloodmesenchymal stromal cells areneuroprotectiveandpromoteregeneration in a rat optic tract model[J]. Exp Neurol,2009,216(2):439-448.
  • 7Jiang B, Zhang P,Zhou D, et al.Intravitreal Transplantation of HumanUmbilical Cord Blood Stem CellsProtects Rats from Traumatic OpticNeuropathy [J]. PLoS One,2013,8?8):1-9.
  • 8Castren M. Neural stem cells [J]. ResultsProbl Cell Differ,2012,54;33-40.
  • 9Guo Y, Saloupis P, Shaw SJ, et al.Engraftment of adult neural progenitorcells transplanted to rat retina injuredby transient ischemia [J]. InvestOphthalmol Vis Sci, 2003,44 (7):3194-3201.
  • 10Zhao LR,Duan WM, Reyes M? et al.Human bone marrow stem cells exhibitneural phenotypes and ameliorateneurological deficits after grafting intothe ischemic brain of rats [J].ExpNeurol,2002,174 (1): 11 -20.

引证文献1

中国医药指南
2011年 第26期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部