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多囊卵巢综合征患者的临床治疗探讨 被引量:2

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摘要 目的:研究分析多囊卵巢综合征(PCOS)患者的临床表现,总结其临床诊断及治疗方案。方法:选取我院2009年7月至2010年7月经诊断为多囊卵巢综合征患者118例,随机分为对照组(去氧孕烯炔雌醇片治疗)和观察组(二甲双胍联合去氧孕烯炔雌醇片治疗)各59例。治疗12周后,对比其体块指数、腰臀围比值、多毛评分及生殖内分泌激素、糖、脂代谢等指标,记录相关数据进行统计分析。结果:观察组治疗前后体重指数、腰臀围比值、多毛评分、黄体生成激素、睾酮、空腹胰岛素、胰岛素抵抗及甘油三酯等对比对照组均明显下降(P<0.01)。治疗12周后,联合用药组黄体生成激素分别从(13.0±4.8)nmol/L降低至(5.0±1.3)nmol/L,两组的睾酮分别从(1.9±0.5)nmol/L降低至(1.0±0.6)nmol/L。结论:二甲双胍联合去氧孕烯炔雌醇片治疗与单纯去氧孕烯炔雌醇片治疗多囊卵巢综合征(PCOS)同样具有临床疗效,但在服药后的不良反应及指标下降幅度上,二甲双胍联合去氧孕烯炔雌醇片治疗效果更为明显,值得在临床上推广应用。
作者 谢梅霞
出处 《医学信息(中旬刊)》 2011年第9期4291-4292,共2页 Medical Information Operations Sciences Fascicule
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