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阿托伐他汀对维持性血透患者血脂及炎性状态的影响 被引量:1

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摘要 目的:观察阿托伐他汀对维持性血液透析(MHD)患者血脂及炎性因子的影响。方法:选择稳定的MHD患者30例,在常规治疗基础上,每晚服用阿托伐他汀钙片,于治疗前及治疗后的12周观察CRP、TC、TG及营养学指标变化,并设20例健康者作为对照组进行比较。结果:患者TC、TG、CRP水平显著高于健康对照组,而营养学指标含量均低于健康对照组。治疗12周后,MHD组TC、TG、CRP水平均较治疗前明显降低(P<0.05),营养学指标均较治疗前增高(P<0.05)。与同期对照组相比,有显著性差异(p<0.05)。结论:他汀类药物治疗可改善MHD患者的微炎症状态及脂代谢紊乱。
作者 周艳
出处 《医学信息(中旬刊)》 2011年第9期4404-4404,共1页 Medical Information Operations Sciences Fascicule
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  • 1Reinhold M, Deppisch W, Hermann G. Complement components as uremic toxins and their potential role as mediators of microinflammation. Kidney Int, 2001,59:271-279.
  • 2Ikeda U, Ileda M, Seiono Y, et al. Interleukin -6 gene transcripts are expressed in atherrosclerotic lesion of the genetically hyperlipidemic rabbits. Atherosclerosis, 1992,92: 213-218.
  • 3Antonio S, Elena M. Cardiac effects of chronic inflammation in dialysis patients. Nephrol Dial Transplant. 2002,17: 10-15.
  • 4Kim K J, Yang WS, Kim SB, et al. Malnutrition, cardiac disease,and mortality: an integrated point of view. Am J Kindey Dis,1998, 32: 834-841.
  • 5Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis,1998; 32: s112-s119.
  • 6Ridker PM, Buring JE, Shin J. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparentl healthy women. Circulation, 1998,98:731-733.
  • 7George A. The microinflammatory state in uremia: causes and potential consequences. J Am Soc Nephrol,2001,12: 1549-1557.
  • 8Vigushin DM, Pepys MB. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest, 1993,91: 1351-1357.
  • 9Simes J, Furberg CD, Braunwald E, Davis BR, Ford I, Tonkin A, et al.Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels.The Prospective Pravastatin Pooling project.Eur Heart J, 2002, 23 (3):207-215
  • 10Scandinavian Simvastatin Survival Study Group.Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease:the Scandinavian Simvastatin Survival Study (4S).Lancet, 1994, 344:1 383-389

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