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乙型肝炎疫苗在无或弱应答人群中的免疫效果分析

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摘要 目的:讨论乙型肝炎疫苗在接种乙型肝炎疫苗后无或弱应答人群中的相关免疫的效果分析,探讨能够提高乙肝免疫接种成功率的措施。方法:根据检验放射免疫方法的测定,测定我院出生的婴幼儿根据0、l、6的接种计划标准接种乙肝疫苗的后的结果,将经过测定为无或弱应答者的的正常健康婴儿72例,按照随机对照原则分为两组,实验组与对照组各31例,两组均重新根据0、l、6接种计划方案再次进行接种,但实验组在接种的同时采用肌注卡介苗素,检测复种前后血清中乙肝表面抗体。结果:采用注射过卡介苗素的实验组的婴幼儿乙肝疫苗的接种率明显的高于对照组,有显著性意义(P<0.01)。结论:卡介苗素通过诱导刺激作用能够升高乙型肝炎疫苗接种成功率,因此在临床应用中,卡介苗素可能逐渐成为一类有效的乙型肝炎疫苗辅助药。
出处 《医学信息(中旬刊)》 2011年第9期4587-4587,共1页 Medical Information Operations Sciences Fascicule
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