阴离子协同组装折叠体

Anions Mediated Foldamers

折叠体研究的目的是设计、合成和表征具有折叠结构的人工合成寡聚物,这些折叠体的折叠结构和自然界中的生物大分子如蛋白质的结构相似但不雷同.折叠体的研究发展为分子识别特别是阴离子识别提供了一个简单而非常有效的工具.本文主要介绍近几年国内外关于阴离子协同组装折叠体的研究进展,探讨了折叠体和阴离子的相互作用规律.

The aims of research in the field of foldamers are to design,synthesize and characterize artificial oligomers with a well-defined folded and compact structure similar but not identical to its natural counterparts such as proteins.Foldamers provide a simple and efficient approach for investigating molecular recognitions in particular anion recognitions,and vice versa these recognitions also can serve for construction of foldamers.The types of hydrogen bond donors,solvation effects,the shape of the anions as well as the complementary between the foldamers and anions have been shown to play crucial roles in the overall foldamer-anions interaction process.The focus of this review is on the recent advances regarding foldamers that self-assemble with the assistance of anions,providing the reader with an introduction to the character of interaction between foldamers and their target anions.