突发性聋治疗策略卫生经济学优化筛选

Optimization and Selection of Sudden Sensorinewal Loss Measurement Combining with Health Economics

目的:评估4种方案治疗突发性聋(SSHL)的经济性。方法:回顾分析4组SSHL治疗方案的疗效及成本-效果:A组:低分子右旋糖酐+复方丹参+地塞米松;B组:A组+金纳多;C组:A组+金纳多+凯时;D组:A组+金纳多+东菱迪夫。结果:4组平均总有效率为65.18%,各组总有效率经比较差异无统计学意义(P>0.05)。SSHL患者的例均及日均住院总费用和药品费用均呈逐年上升趋势。各组成本-效果比依次为:A组33.82元、B组48.93元、C组67.90元、D组93.50元。结论:SSHL 4组治疗方案的治疗效果差异无统计学意义。A方案为成本-效果最佳方案。

Objective： To evaluate the pharmacoeconomic of 4 therapies in treatment of sudden sensorineural hearing loss（SSHL）.Methods： 444 patients with SSHL were randomly divided into four groups,which were group A： Dextran and Salvia and Dexamethasone（DXM）;group B： Dextran and Salvia and DXM and Ginaton;group C： Dextran and Salvia and DEX and Ginaton and prostaglandin El;and group D： Dextran and Salvia and DEX and Ginaton and batroxobin.The cost-effectiveness of the four groups were compared.Results： A comparison of efficacy among different groups showed an average total effective rate of 65.18%.There was no statistic significance in the total effective rates of the four groups（P0.05）.The average total cost of hospitalization per case and per day,the average total drug cost per case and per day increased annually.The ratio of cost-effectiveness of the four groups are 33.82,48.93,67.90 and 93.50 yuan respectively.Conclusion： There is no statistical significance in efficacy among the four therapies on SSHL.Out of the four therapeutic regimens,regimen A shows best cost-effectiveness.