期刊文献+

钙稳态调节蛋白1基因与阿尔茨海默病的相关性 被引量:1

原文传递
导出
摘要 虽已明确载脂蛋白E(ApoE)ε4等位基因是晚发性阿尔茨海默病(LOAD)的主要危险因素之一,但流行病学研究显示有42%-68%的LOAD不携带ApoE ε4等位基因,提示还有其他因素在LOAD的发病中发挥作用。
出处 《中华神经科杂志》 CAS CSCD 北大核心 2011年第9期601-601,共1页 Chinese Journal of Neurology
  • 相关文献

参考文献1

  • 1Pei-Jing Cui, Lan Zheng, Li Cao, et al. CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in the Chinese population. J Alzheimers Dis, 2010,19 :31-35.

同被引文献13

  • 1卜碧涛,张旻,王伟,Inez Vincent.14-3-3蛋白与阿尔茨海默病tau蛋白异常磷酸化的关系[J].中华神经科杂志,2005,38(10):620-623. 被引量:13
  • 2Elgh E, Lindqvist AA, Fagerlund M, et al. Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimer' s disease. Biol Psychiatry, 2006, 59 : 155-161.
  • 3Green KN, Billings LM, Roozendaal B, et al. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer' s disease. J Neurosci, 2006, 26: 9047-9056.
  • 4Sotiropoulos I, Catania C, Riedemann T, et al. Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau. J Neurochem, 2008, 107: 385-397.
  • 5Clevers H. Wnt/beta-catenin signaling in development and disease. Cell, 2006, 127 : 469-480.
  • 6Boonen RA, van Tijn P, Zivkovic D. Wnt signaling in Alzheimer's disease: up or down, that is the question. Ageing Res Rev, 2009, 8 : 71-82.
  • 7Liu XA, Liao K, Liu R, et al. Tau dephosphorylation potentiates apoptosis by mechanisms involving a failed dephosphorylation/ activation of Bcl-2. J Alzheimers Dis, 2010, 19: 953-962.
  • 8Mcgowan E, Efiksen J, Hutton M. A decade of modeling Alzheimer' s disease in transgenic mice. Trends Genet, 2006, 22 : 281-289.
  • 9Yu G, Li Y, Tian Q, et al. Berberine attenuates calyculin A- induced cytotoxieity and Tau hyperphosphorylation in HEK293 ceils. J Alzheimers Dis, 2011, 24: 525-535.
  • 10Roberson ED, Scearce-Levie K, Palop JJ, et al. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer' s disease mouse model. Science, 2007, 316: 750- 754.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部