动物慢性砷中毒的毒理病理学研究进展

Research of Toxicological Pathology on Animals' Arsenicalism

砷制剂由于在提高增重和改进饲料利用率方面的作用而被广泛应用于畜禽生产,长期使用或剂量不当,会导致动物砷的慢性中毒,通过食物链的富集作用,导致人类相应疾病的发生。慢性砷中毒可以导致皮肤损伤、心血管疾病、泌尿系统及神经系统损伤、糖尿病等,砷还是一种确定的致癌物。文章对动物慢性砷中毒的毒理病理学进行了综述,并对慢性砷中毒可能的研究方向进行了展望。

Arsenic preparations has been widely used in the production of livestock just because its effect on increasing weight and improving the feed efficiency,however,long-term use or improper dosage can cause chronic poisoning of arsenic in animals.Then it can lead to the corresponding disease of human through the enrichment of food chain.Chronic arsenic poisoning can cause skin damage,cardiovascular disease,urinary system and neurological damage and diabetes,what＇s more,arsenic is also a certain carcinogens.The article summarizes on the poisoning toxicological pathology of animal＇s arsenicalism and outlooks the possible research directions of arsenicalism.