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脂联素对Ⅱ型糖尿病患者伴牙周炎的影响 被引量:4

The influence of adiponectin on type Ⅱ diabetes patients with periodontitis
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摘要 脂联素是目前发现的对人体有保护作用的脂肪细胞特异分泌的激素蛋白,具有降糖、增加胰岛素敏感性、抗炎、抗动脉粥样硬化和调节骨代谢的作用,是Ⅱ型糖尿病的保护性因子。牙周炎被认为是糖尿病的第六并发症,两者相互影响。脂联素与牙周炎的相互作用尚不明了,本文就脂联素与Ⅱ型糖尿病合并牙周炎的相关性研究现状进行综述,以期为今后的治疗及研究提供一种新思路。 We recently showed that adiponectin,an adipocyte derived cytokine,may function as a type Ⅱ diabetes protective factor.It had an effect of lowering blood glucose,increasing insulin sensitivity,anti-inflammatory,anti-atherosclerosis and regulating the bone metabolism.Periodontitis is considered as the sixth complication of diabetes.Some researches indicated that there lies a close relationship between periodontitis and diabetes,which often influence each other.The interaction of adiponectin and periodontitis is not clear.In this review,in order to acquire a new therapy of periodontitis in the future,the influence of adiponectin on type Ⅱ diabetes patients with periodontitis will be discussed.
出处 《国际口腔医学杂志》 CAS 2011年第5期607-610,共4页 International Journal of Stomatology
基金 复旦大学青年基金资助项目(EYF151040)
关键词 脂联素 Ⅱ型糖尿病 牙周炎 adiponectin type Ⅱ diabetes periodontitis
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参考文献32

  • 1Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associat- ed with both lipoatrophy and obesity[J]. Nat Med, 2001, 7 (8) : 941-946.
  • 2Staiger H, Kaltenbach S, Staiger K, et al. Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and li- pid metabolism[J]. Diabetes, 2004, 53(9):2195-2201.
  • 3Yamamoto Y, Hirose H, Saito I, et al. Adiponectin, an adipocyte-derived protein, predicts future insulin resis- tance: Two-year follow-up study in Japanese population [J]. J Clin Endocrinol Metab, 2004, 89(1):87-90.
  • 4Yang WS, Jeng CY, Wu TJ, et al. Synthetic peroxisome proliferator-aetivated receptor-gamma agonist, rosiglita- zone, increases plasma levels of adiponeetin in type 2 diabetic patients[J]. Diabetes Care, 2002, 25 (2)7376- 380.
  • 5Statniek MA, Beavers LS, Conner LJ, et al. Decreased expression of apMl in omental and subcutaneous adipose tissue of humans with type 2 diabetes[J]. Int J Exp Di- abetes Res, 2000, 1 (2) : 81-88.
  • 6Lihn AS, Ostergard T, Nyholm B, et al. Adiponectin ex- pression in adipose tissue is reduced in first-degree rel- atives of type 2 diabetic patients[J]. Am J Physiol En- doerinol Metab, 2003, 284 (2):E443-E448.
  • 7Maeda N, Shimomura I, Kishida K, et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 [J]. Nat Med, 2002, 8(7):731-737.
  • 8王遂军,贾伟平,包玉倩,陆俊茜,方启晨,陈蕾,陆惠娟,项坤三.血清脂联素与肥胖的关系[J].中华内分泌代谢杂志,2005,21(1):36-38. 被引量:89
  • 9Matsuda M, Shimomura I, Sara M, et al. Role of adipo- nectin in preventing vascular stenosis. The missing link of adipo-vascular axis[J]. J Biol Chem, 2002, 277 (40): 37487-37491.
  • 10Okamoto Y, Arita Y, Nishida M, et al. An adipocyte- derived plasma protein, adiponectin, adheres to injured vascular walls[J]. Horm Metab Res, 2000, 32(2):47-50.

二级参考文献21

  • 1卢慧玲,王宏伟,Katherine Cianflone,温宇,林汉华.肥胖症儿童血浆脂联素、促酰化蛋白水平变化的临床意义[J].中华内分泌代谢杂志,2004,20(6):499-501. 被引量:7
  • 2贾伟平,项坤三,吴松华,杨世埙,潘晓平,王延庆,何进卫,唐峻岭,严钱勤,薛凤仙,翁青.腹内型肥胖的代谢特点及合并NIDDM后的变化[J].中国糖尿病杂志,1995,3(1):11-14. 被引量:31
  • 3韩桃娟 赵瑞芳 周以钧等.用逐步回归法分析牙周病是否与糖尿病有关[J].华西口腔医学杂志,1985,3(4):229-231.
  • 4Grossi SG, Genco RJ. Periodontal disease and diabetes mellitus: a two-way relationslip, Ann Periodontol, 1998,3(1):51-61.
  • 5Rodrigues DC, Taba MJ, Novaes AB, et al.Effect of non-surgical periodontal therapy on glycemic control. 2003,74(9):1361-1367.
  • 6Nishimura F, Kono T, Fujimoto C,et al.Negative effects of chronic inflammatory periodontal disease on diabetes mellitus, J Int Acad Periodontol.2000,2(2):49-55.
  • 7Tervone T, Knuuttila M. Relation of diabetes control to priodontal pocketing and alveolar bone level. Oral Surg Oral med Oral pathol.1986,61(4):346-349.
  • 8Tarlor GW, Burt BA, Becker MP,et al. Severe periodontitis and risk for poor glycemic control in patients with non-insulin-dependent diabetes mellitus.J periodontol.1996,67(10):1085-1093.
  • 9Mealey BL, Rathman MP. Periodontal disease and diabetes mellitus. Bidirectional relationship .Dent Today. 2003,22(4):107-113.
  • 10Iwamoto Y, Nishimura F, Nakagawa M, et al.The effect of antimicrobial periodontal treatment on circulating tumor necrosis factor -alpha and glycated hemoglobin level in patients with type 2 diabtes .J Periodontol.2001,72(6):774-778.

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