肺癌患者血清中表皮生长因子受体、HER-2、U1-AsnRNP、p53自身抗体研究进展

Advances of EGFR, HER-2,U1-A snRNP and p53 autoantibodies in serum of lung cancer patients

新近的研究表明，在多种肿瘤包括肺癌患者的血清中，均可检测到针对肿瘤相关抗原的自身抗体。表皮生长因子受体抗体、HER-2抗体、U1-AsnRNP、p53抗体是近年来发现的在肺癌早期诊断中有重要意义的自身抗体，又因为血清中自身抗体检测方便，故上述自身抗体有望成为肺癌早期诊断中重要的分子标志物。

Recent studies have shown that tumor-associated antigen autoantibodies can be detected in the serum of multiple tumor patients, including lung cancer. EGFR ,antibody, HER 2 antibody, U1-A snRNP antibody and p53 antibody are found in the early diagnosis of lung cancer in recent years, and because the detection of autoantibodies is convenient, so these antibodies is expected to become important molecular markers in the early diagnosis of lung cancer.