步长稳心颗粒对老年舒张性心力衰竭合并阵发性房颤患者P波离散度的影响

The effect of Buchangwenxin particle on dispersion of P wave in elder patients with diastolic cardiac dysfunc-tion and paroxysmal atrial fibrillation

研究稳心颗粒对老年舒张性心力衰竭合并阵发性心房颤动（PAF）患者P波最大时限（Pmax）、P波离散度（Pd）的影响。方法将115例老年舒张性心力衰竭合并PAF患者作为房颤组，随机分为两组：A组56例为常规治疗组，B组59例在常规治疗的基础上加用稳心颗粒。同时以54例老年舒张性心力衰竭不伴PAF患者作为对照组。比较房颤组及无房颤组以及A、B组间治疗前后Pmax及Pd的变化。结果房颤组Pmax及Pd均高于非房颤组（均P〈0．01），治疗前A、B两组Pmax及Pd差异均无统计学意义（均P〉0．05），治疗后B组房颤发作次数明显减少，Pmax及Pd较治疗前均明显缩短，与A组比较差异均有统计学意义（均P〈0．01）。结论老年舒张性心力衰竭合并PAF者较无PAF者Pmax及Pd增大，步长稳心颗粒治疗老年舒张性心力衰竭合并PAF可缩短Pmax及Pd，减少房颤发作次数。

To investigate the effect of Buchangwenxin particles in maximum P wave（Pmax） ,dis- persion of P wave（Pd） of elder patients with diastolic cardiac dysfunction and paroxysmal atrial fibrillation（ PAF）, Methods 115 elder patients with diastolic cardiac dysfunction and PAF were randomly divided into two groups： group A received the routine drug therapy,and group B received Buchangwenxin particles with routine drug therapy. Another 54 elder patients with diastolic cardiac function but without PAF was selected as control group. Changes in Pmax and Pd were compared between groups with or without PAF as well as subgroups. Results Pmax and Pd were wider in PAF group than no PAF group（ all P 〈0.01 ）. There was no difference between group A and B in Pmax and Pd（all P 〉0.05） ,and there were less atrial fibrillation as well as shortened Pmax and Pd in group B,whieh was sig- nificantly different with group A（ all P 〈 0. O1 ）. Conclusion Pmax and Pd were wider in eider patients with diastolic cardiac dysfunction and PAF than those without PAF, and Buchangwenxin particles could shorten Pmax and Pd and reduce the attacks of atrial fibrillation.