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重型颅脑损伤患者血清载脂蛋白E的变化及意义 被引量:2

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摘要 观察重型颅脑损伤患者血清载脂蛋白E(ApoE)的变化,并探讨其临床意义。方法采用酶法分别检测50例中型和重型颅脑损伤患者入院24h内血清ApoE水平,与健康对照组进行比较。结果重型颅脑损伤组、中型颅脑损伤组和健康对照组ApoE的水平分别为(63.06±10.05)mg/L、(40.81±7.90)mg/L和(41.09±8.77)mg/L。重型颅脑损伤组ApoE水平明显高于中型颅脑损伤组和健康对照组,差异有统计学意义(t=12.186,11.848;均P〈0.05),中型颅脑损伤组ApoE水平与健康对照组差异不明显(t=0.284,P〉0.05)。结论重型颅脑损伤患者血清ApoE明显升高,中型颅脑损伤患者血清ApoE无明显变化,提示颅脑损伤时ApoE可作为评价病情严重程度的一个参考指标。
出处 《中国基层医药》 CAS 2011年第20期2793-2794,共2页 Chinese Journal of Primary Medicine and Pharmacy
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