精索多形性脂肪肉瘤1例报告并文献复习

Liposarcoma of the Spermatic Cord:Report of A Case and Review of the Literature

目的:分析并总结精索脂肪肉瘤患者的临床表现及其诊断及治疗方法。方法:回顾性分析我院收治的1例精索脂肪肉瘤患者的临床资料:左侧阴囊内有一9.0 cm×9.4 cm×6.7 cm肿块,B超检查示左侧阴囊内存在一非均质实性包块;MRI显示左侧阴囊内有实质性肿瘤,未见肿大淋巴结。血清肿瘤标志物β-HCG、CEA、PSA和AFP检查均无异常。手术切除肿瘤的同时行左侧阴囊部分切除术。结果:术后病理检查提示为多形性混合型脂肪肉瘤。患者术后恢复顺利。结论:精索脂肪肉瘤是一种罕见的泌尿生殖系肿瘤,诊断主要依据病理检查结果确定;治疗以根治性睾丸切除术为主要方式,辅助放疗、化疗疗效不确切;预后与肿瘤组织病理类型密切相关,局部复发很常见,需长期随访。

Objective： To analyze and summarize the clinical manifestations, diagnosis and treatment of the spermatic cord liposarcoma. Methods： Retrospective analysis of 1 case of spermatic cord liposarcoma of our hospital patient＇s clinical data： There was a 9.0 cm×9.4 cm×6.7 cm mass in the left scrotum. An ultrasound scan confirmed the presence of a solid mass of uniform homogeneity in the left scrotum. MRI revealed a solid mass localized within the left scrotum and no lymph node metastasis was found. All the serum analyses including β-HCG,CEA, PSA and AFP were normal. Radical tumor resection and partial left scrotum resection were performed. Results.. Pathological examination revealed spermatic cord pleomorphic liposarcoma. The patient was well recovered after surgery. Conclusions： Liposarcoma of spermatic cord is a rare genitourinary tumor. The diagnosis of spermatic cord liposarcoma depends on the pathological examination. The main treatment is radical orchiectomy. The effect of radiotherapy and chemotherapy is not clear. The prognosis is closely related to tumor histological type, local recurrence is common, so this disease requires long-term follow-up.