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内质网-线粒体对话在非酒精性脂肪性肝病发病机制中的作用 被引量:3

Cross-talk between endoplasmic reticulum and mitochondria in non-alcoholic fatty liver disease
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摘要 非酒精性脂肪性肝病(NAFLD)是指无过量饮酒史、以甘油三酯在肝内过度沉积为基础的慢性肝脏疾病,可进一步发展为肝硬化、肝衰竭甚至肝癌等终末期肝病。迄今,对NAFLD的发生机制尚未阐明。了解内质网与线粒体的相互对话(cross—taLk)对进一步理解NAFLD的发病机制及寻求有效的治疗方式具有重要的意义。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2011年第9期648-650,共3页 Chinese Journal of Hepatology
关键词 脂肪肝 内质网 线粒体 发病机制 Fatty liver Endoplasmic reticulum Mitochondria Pathogenesy
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