桥本病合并甲状腺癌临床分析

Clinical analysis of Hashimoto's disease coexisted thyroid carcinoma

目的探讨桥本病合并甲状腺癌的临床特征。方法通过回顾2001-2010年手术治疗的17例桥本病合并甲状腺癌的临床资料,总结外科治疗的适应证、方法和结果。结果 17例均为甲状腺乳头状癌,男3例,女14例,平均年龄41岁,发病率为12.9%,无1例死亡。结论对桥本病合并孤立的甲状腺肿块有恶性可能、甲状腺重度肿大产生压迫症状、合并疼痛,甲状腺素治疗无效的桥本病患者应积极手术治疗。术中冰冻病理切片为恶性,依照甲状腺癌的处理原则来决定手术方式;术后患者应给予甲状腺素治疗。

Objective To discuss the clinical characteristics and diagnosis of Hashimoto＇s disease coexisted thyroid carcinoma.Methods 17 cases diagnosed as Hashimoto＇s disease coexisted thyroid carcinomaby histologic examination at our hospital from 2001 to 2010 were analyzed,concluding their indications,management and effectiveness.Results They were all papillary thyroid carcinoma,There were 3 male and 14 females with average age of 41 years.The incidence of Hashimoto＇s disease associated with thyroid cancer was 12.9%.No operative mortality was found.Conclusion It must be given surgical operation to single neoplasm of the Hashimoto＇s disease under suspicion,thyroid seriously enlarged with pressure symptoms,thyroid enlarged with pain and medication is ineffective,intraoperative frozen section is a reliable and may guide us the surgical method,the treatment of Hashimoto＇s disease coexisted thyroid carcinoma is the same as the thyroid carcinoma,and patients must give medical treatment.