心肺脑复苏时联合应用肾上腺素和纳洛酮

Study of Combined Use of Epinephrine Combined with Naloxone Hydrochloride during Cardiopulmonary Resuscitation

目的:评价心肺脑复苏时联合应用肾上腺素和纳洛酮的疗效。方法:回顾分析55例心跳骤停患者临床资料,各例均常规行心肺脑复苏。分为2组,研究组联合应用肾上腺素、纳洛酮,对照组仅予标准剂量肾上腺素治疗。结果:与对照组比较,研究组总有效率显著升高(P<0.05),自主呼吸循环恢复时间显著缩短(P<0.05)。结论:联合应用肾上腺素、纳洛酮可提高心肺脑复苏成功率。

Objective：To investigate the therapy effects of combined use of epinephrine with naloxone during cardiopulmonary resuscitation.Methods： Fifty-five patients with cardiac arrest were divided into control group and observation group randomly.Twety-seven cases in control group were given standard-dose epinephrine,and twenty-eight cases in observation group were given epinephrine combined with naloxone hydrochloride.The rate and time of spontaneous respiration restoration,spontaneous circulation restoration,the survival rate take advantage in observation group contrast to control group.Results： The rate of spontaneous respiration restoration and spontaneous circulation restoration and the survival rate after discharge in the observation group were significantly higher than those in the control group.and the average time of spontaneous circulation restoration and spontaneous respiration restoration in the observation group was shorter than that in the control group.Conclusions： The combination of epinephrine with naloxone may significantly increase the success rates of cardiopulmonary resuscitation.