子宫颈环形电切术治疗宫颈上皮内瘤样病变的疗效

Clinical Analysis of Cervical Intraepithelial Neoplasia Treated by Loop Electrosurgical Excision Procedure

目的:观察宫颈电环切除术(LEEP)治疗不同级别宫颈上皮内瘤变(CIN)的疗效。方法:对宫颈薄层液基细胞学(TCT)检查结果为不典型鳞状上皮(ASC)以上,阴道镜下活检诊断为宫颈CINⅠ级75例、宫颈CIN II级21例、CIN III级2例患者行LEEP治疗,组织标记后行病理检查。LEEP术后每3个月以液基细胞学和阴道镜检查方法随访所有的患者。结果:术后3个月随访,宫颈糜烂100%愈合,宫颈细胞检查阴性96例,核异质2例,Leep治愈率可达97.9%。术后9个月复查均阴性,无复发病例。结论:LEEP是目前临床上诊治CIN的有效方法。

Objective：To investigate the efficacy of loop electrosurgical excision procedure（LEEP） for the treatment of cervical intraepithelial neoplasia（CIN）.Methods： A total of 98 patients with CIN diagnosed by thinprep liquid-based cytology test（TCT） and biopsy guided by colposcopy were treated by LEEP,and the specimens were marked for further pathological examination.Among the 98 cases,75 cases were diagnosed as stage one CIN（CIN I）,21cases as CIN II and 2 cases as CIN III.Three months after LEEP,all 98 patients were follow-up visited by TCT and colposcopy.Results： 100% patients with cervical erosion were cured.Among 98 cases who were re-checked three months after operation,96 patients showed normal appearance by TCT,and only 2 patients showed dyskaryosis.The cure rate of LEEP was 97.9%.There were no abnormity and recurrence nine months after LEEP operation.Conclusions： LEEP is an effective clinical method for the diagnosis and treatment of CIN.