用于血液净化疗法的WP系列体外循环血路管临床应用的有效性及安全性研究

Efficacy and Safety of WP Series Extracorporeal Blood Tube Used in Blood Purification Therapy

目的:评价临床应用WP系列体外循环血路管的有效性及安全性。方法:分析临床应用血液透析用和床旁血液滤过用血路管时的血液净化治疗成功情况及患者症状、体征和实验室检查结果变化情况。结果:分别用床旁血液滤过用血路管和血液透析用血路管各治疗10例次,均顺利完成预定时间治疗。所有血路管的外观透明度、光洁度和柔软度均较好。治疗前后患者血白细胞计数、中性粒细胞比例及内毒素水平均无显著变化。在应用血液透析用血路管治疗中,2例患者出现肌肉抽搐,1例出现透析低血压,经对症处理后均好转。未发现其他不良事件。结论:WP系列血路管在血液净化治疗中有较好的可靠性和安全性。

Objective：To evaluate the efficacy and safety of WP series extracorporeal blood tubes in blood purification therapy.Methods： Observational study was used to evaluate the symptoms,signs and the diversification of laboratory data in patients treated by WP series blood tubes.Results： Patients were treated respectively for 10 sessions by hemodialysis blood tube or continuous hemofiltration blood tube.All patients successfully finished the treatment schedule at the end.Transparency,smoothness and softness of the tested blood tube were very good.White blood cell count,neutrophil percentage and endotoxin level didn＇t change significantly before and after therapy（P0.05）.During the period of therapy,two patients suffered from muscle cramps and one patient suffered from intradialysis hypotension when treated by hemodialysis blood tube.These patients fully recovered after symptomatic treatment.Other adverse events didn＇t found during the period of study.Conclusions： The efficacy and safety of tested WP series blood tube are very good when used in hemodialysis therapy or continuous hemofiltration therapy.