益肾通治疗肾虚瘀滞型前列腺增生的临床疗效观察

Clinical Observation of Therapeutic Effect of Yishentong Capsules for Hyperplasia of Prostate with Kidney Deficiencyand Blood-stasis Stagnation

【目的】观察应用益肾通胶囊治疗肾虚瘀滞型良性前列腺增生的临床疗效。【方法】将门诊符合纳入标准的56例前列腺增生患者随机分成2组,治疗组30例应用益肾通胶囊(肉苁蓉、北芪、王不留行、泽兰等)口服,每次4粒,每日3次;对照组26例应用泽桂癃爽胶囊,每次2粒,每日3次;2组均以30 d为1个疗程,共治疗3个疗程,观察治疗前后患者的国际前列腺症状评分(I-PSS评分)、经腹壁B超示残余尿量(VPRV)、最大尿流率(qv,m ax)等的变化。【结果】治疗后2组患者的I-PSS症状评分均降低、VPRV均减少、qv,m ax均增大,与治疗前比较差异均有显著性意义(P<0.05),但治疗后2组间比较差异无显著性意义(P>0.05),表明2组疗效相当。此外,在本研究临床观察病例中均未发现明显不良反应。【结论】益肾通胶囊可以改善肾虚瘀滞型前列腺增生患者的临床表现,其疗效与泽桂癃爽胶囊相当。

Objective To observe the therapeutic effect of Yishentong Capsules （YC） for hyperplasia of prostate with kidney deficiency and blood-stasis stagnation. Methods Fifty-six qualified outpatients were randomized into two groups. The treatment group （N = 30） was given YC （mainly composed of Herba Cistanches, Radix Astragali, Semen Vaccariae, Herba Lyeopi, etc） orally, 4 capsules each time, rid. The control group （N = 26） was given Zegui Longshuang Capsules orally, 2 capsules each time, rid. Thirty days constituted one treatment course, and the treatment lasted 3 courses. The international prostate symptom score （I-PSS） was evaluated, and residual urine volume and maximum urine flow rate showed by abdominal wall B-type uhrsonography were examined before and after treatment. Results I-PSS was decreased, residual urine volume was reduced, and maximum urine flow rate was increased in the two groups after treatment （P 〈 0.05 compared with those before treatment） , the differences of the above parameters were insignificant between the two groups （P 〉 0.05）. No obvious adverse reaction was found during the observation. Conclusion YC has an effect on relieving symptoms and signs in hyperplasia of prostate patients with kidney deficiency and blood-stasis stagnation, and its therapeutic effect is similar to that of Zegui Longshuang Capsules.