摘要
阿克苷为苯丙素苷类单体化合物,属天然多酚类成分,可从多种植物中分离提纯得到。阿克苷具有强抗氧化作用,可通过清除自由基、抑制细胞色素P450 2E1等作用和(或)协同超氧化物歧化酶、谷胱甘肽等抗氧化物质对抗氧化应激,从而保护因氧化应激造成的细胞和生物大分子损伤,对阿克苷的生理活性研究可为开发新一类抗机体氧化药物提供科学依据。
Acteoside is one of phenylpropanoid glycosides isolated from diverse natural vegetation.The present studies have reported the acteoside possesses the effect of antioxidant.It protects the cells and biological macromolecules from the oxidative damage through inhibiting the oxidizing agents such as ROS and cytochrome P450 2E1 and/or restore the antioxidant agents such as SOD,GSH.The further research of acteoside physiological activity can provide scientific basis for developing a new category of anti-oxidative drugs.
出处
《医学综述》
2011年第18期2721-2723,共3页
Medical Recapitulate
基金
国家自然科学基金(81060077)
关键词
阿克苷
苯丙素苷
抗氧化
天然产物
Acteoside
Phenylpropanoid glycoside
Antioxidant
Natural product
