左炔诺孕酮宫内缓释系统治疗子宫腺肌病研究进展

Research of Levonorgestrel-releasing Intrauterine System Treatment for Adenomyosis

左炔诺孕酮宫内缓释系统作为一种新型激素宫内避孕系统,长期有效释放左炔诺孕酮发挥作用。近年来发现其除了具有长期避孕作用外,对一些妇科疾病具有治疗作用,尤其在子宫腺肌病的治疗中,具有疗效明显、作用时间长及不良反应小等优点。现就近年来左炔诺孕酮的作用机制及在临床上的应用进展进行综述。

Levonorgestrel-releasing intrauterine system is a new hormonal intrauterine contraceptive system.The system have the long-term effective in releasing levonorgestrel.In recent years,it found that in addition to long-term contraceptive effects,the system also can treat some gynecological diseases,especially in the treatment of adenomyosis,with efficacy,long term effective and low side effects,etc.The mechanism of levonorgestrel and the progress in the clinical application in recent years were reviewed in this paper.