2-亚磷酸二乙酯基杂环烯酮缩胺类化合物的合成

Synthesis of 2-Diethyl Phosphate Heterocyclic Ketene Aminals

用廉价易得原料Mn(OAc)2-KMnO4体系代替昂贵的Mn(OAc)3催化二甲缩硫醚(1)与亚磷酸二乙酯反应获得结构新颖的2-亚磷酸二乙酯基缩硫醚化合物2a～2d.然后,化合物2a～2d与二胺类化合物3反应以较高产率合成了一系列2-亚磷酸二乙酯基杂环烯酮缩胺(4).

Mercaptals（1）,with low-cost and readily available Mn（OAc）2-KMnO4 system instead of the expensive Mn（OAc）3 as catalyst,reacted with diethyl phosphite to give novel 2-diethyl phosphate mercaptals 2a～2d.Sequentially,compounds 2a～2d reacted with diamines 3 to afford a series of 2-diethyl phosphate heterocyclic ketene amines（4） with good yields.