糖尿病性偏侧舞蹈症12例临床分析

Clinical analysis of twelve cases with diabetic hemichorea

目的探讨糖尿病性偏侧舞蹈症的临床表现、发病机制、影像学改变及预后。方法回顾性分析我院2005—2010年收治的12例糖尿病性偏侧舞蹈症患者的临床表现、影像学改变、实验室检查结果及治疗过程。结果糖尿病性偏侧舞蹈症见于血糖长期未控制的糖尿病患者。酮症和非酮症均可发病。头颅CT和（或）头颅MRI检查对本病诊断有意义，尤其头颅MRITIWI高信号且无水肿影，边缘清楚，无占位效应。经治疗干预后患者舞蹈样动作持续7d-4年后均停止。结论提高临床医师及影像学工作者对糖尿病性偏侧舞蹈症的认识，减少对本病的误诊，可使患者得到及时治疗。

Objective To explore the clinical manifestations, pathogenesis, radiographic features and prognosis of Diabetic Hemichorea. Methods We conducted a retrospective analysis in 12 patients suffering Diabetic Hemichorea in terms of the clinical manifestations, radiographic features,laboratory results and treatment processeswho were hospitalized in our hospital from 2005 to 2010. Results Diabetic Hemichorea occurred mostly in the patients with diabetics with uncontrolled blood glucose level for a long term. Both ketosis and nonketosis patients can suffer this disease. Cranial CT and/or MRI imaging, especially those with high signal and clear border in MRIT1WI but without edema shadow and mass effect, was of diagnostic value. The symptoms vanished 7 day to 4 years after the treatment. Conclusion Deepening the understanding of clinicians and imageological staff upon Diabetic Hemichorea can decrease the misdiagnosis and ensure timely treatment for this disease.