摘要
2011年5月以来,德国暴发了由肠出血性大肠杆菌O104:H4感染引起的疫情,世界多个国家相继报告有此类病例发生,这是首次报告由肠出血性大肠杆菌O104:H4感染引起疾病的暴发流行。截至2011年6月24日,已造成3920例感染和48例死亡[1]。该病患者以血水样腹泻、呕吐起病,部分病例并发溶血性尿毒综合征,导致多器官受损,甚至死亡。疫情发生后,世界各国相关学者立即开展其病原学特性研究,同时迅速研制出实验室检测方法和试剂,为该病的及时诊断、治疗和疫情控制发挥了很大作用。本文介绍了肠出血性大肠杆菌O104:H4病原学及其检测方法的研究进展。
Since May 2011, Enterohaemorrhagic Escherichia coli（EHEC） O104：H4 has caused a large outbreak of epidemic in Germany. Then some similar cases have been reported in other countries. It is the first outbreak caused by EHEC O104. By 24th June 2011, this outbreak has caused 3920 infections and 48 deaths. The onset of symptoms of the disease caused by EHEC are bloody diarrhoea and vomiting. Some cases may develop to haemolytic uraemic syndrome （HUS）, which lead to multiple organ damage or even death. After the outbreak, the scientists in the world have studied the etiology characteristics and established laboratory detection and reagents in a short time, which plays a large role in the preventing, treating and controlling the EHEC O104 infection. The etiology characteristics of EHEC O104 and detection methods were introduced in this paper.
出处
《中国国境卫生检疫杂志》
CAS
2011年第4期272-275,共4页
Chinese Journal of Frontier Health and Quarantine
基金
国家质检总局科研基金项目(2010IK128)
