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替米沙坦对老年高血压治疗效果观察 被引量:1

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摘要 目的:探讨替米沙坦治疗老年高血压的临床疗效。方法:选择194例高血压患者,采用替米沙坦片40mg,1次/日,若降压效果欠佳时,第2周加量,80mg/日,早晚间隔12小时服药,服药后前3天每日早晚9:00测血压1次。结果:194例经过治疗显效142例,显效率73.2%,有效35例,有效率18.0%,无效17例,无效率8.8%,总有效率为92.2%。194例患者治疗前收缩压:163.2±24.6mmHg,舒张压:102.8±9.8mmHg,在服药后3天内血压无明显下降,服药1周血压明显下降,服药4周和8周血压比服药1周水平的略微下降,收缩压平均下降24.1mmHg,舒张压平均下降15.6mmHg。结论:替米沙坦治疗高血压疗效显著,值得推广。
作者 赵冰
出处 《中国社区医师(医学专业)》 2011年第26期83-83,共1页
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  • 1区晋禧.肾上腺素β-受体阻滞剂在心血管疾病中应用的进展[J].临床心血管病杂志,1994,10(1):53-55. 被引量:40
  • 2李德之.心力衰竭时β-阻滞剂应用的原则与经验[J].中国实用内科杂志,1994,14(2):75-76. 被引量:70
  • 3Siragy H. Angiotensin II receptor blockers: review of the binding characteristics. Am J Cardiol, 1999, 84: 3S-8S.
  • 4Neutel JM, Smith DHG. Dose response ane antihypertensive efficacy of the AT1 receptor antagonist telmisartan in patients with mild to moderate hypertension. Adv Ther, 1998, 15: 206-217.
  • 5Myers MG. Suggested guidelines for determining the trough-to-peak ratio of antihypertensive drugs. Am J Hypertens, 1996, 9: 76S-82S.
  • 6Mallion JM, Siche JP, Lacourciere Y, et al. ABPM comparison of antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension. J Hum Hypertens, 1999, 13: 657-664.
  • 7Lipicky RJ. Trough/peak ratio: the rationale behind the United States Food and Drug Administration reco mmendations. J Hypertens, 1994, 12(Suppl 8): S17-S19.
  • 8Zannad F, Matzinger A, Larche J. Trough/peak ratios of once-daily angiotensin converting enzyme inhibitors and calcium antagonists. Am J Hypertens, 1996, 9: 633-643.
  • 9Muller JE, Ludmer PL, Willich SN, et al. Circadian variation in the frequency of sudden cardiac death. Circulation, 1987, 75: 131-138.
  • 10The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the cooperative north scandinavian enalapril survival study (CONSENSUS). N Engl J Med, 1987,316:1429 - 1435.

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