芦荟汁对大鼠实验性肠炎的干预作用

Effect of Aloe Juice on Experimental Colitis in Rats

本研究以芦荟汁灌胃实验性肠炎大鼠以探究芦荟汁对实验性肠炎的干预作用.结果表明,对照组和芦荟汁灌胃组大鼠体重均呈增长趋势,而肠炎模型组大鼠体重增长迟缓;芦荟汁灌胃大鼠的胸腺脏器系数明显小于对照组和肠炎模型组;对照组直肠长度显著长于其它各组,而肠炎模型组大鼠直肠长度显著短于芦荟灌胃组;对照组结肠粘膜颜色呈正常的淡粉色,肠炎模型组可见较大面积的糜烂肿胀与炎症形态,而芦荟汁灌胃组大鼠肠粘膜未见明显的糜烂肿胀与炎症形态,颜色也较为正常,但可见局部有明显肥大.实验结果提示芦荟汁对大鼠实验性肠炎有一定的干预作用.

In this paper,the intervention effect of Aloe juice on experimental colitis in rats was studied.The results showed that the body weight gain of rats in control group and in Aloe juice treatment groups was a little high than that of in colitis model group.The organ coefficient of thymus in Aloe juice treatment groups was markedly lower than that of in control group and colitis model group.The length of colon in control group was much longer than that of in other groups.The colon length in of Aloe juice treatment groups was longer than that of in colitis model group.Colonic mucosa in control group showed normal pink,and no mucosa inflammation and ulcer were observe.Compared with the control group,colonic mucosa in the of Aloe juice treatment groups showed red,and local pathological thickening and no severe mucosa inflammation and ulcer can be seen.Compared with Aloe juice treatment groups,the colonic mucosa in the colitis model group showed pathological dark brown,and severe mucosa damage can been seen which include mucosa inflammation,erosion and ulcer.The results demonstrated that Aloe juice could relieve the pathological changes of experimental colitis in rats.