分子系统生物学与细胞发生动力学

Molecular Systems Biology and Dynamics of Cytogenesis

系统生物学采用系统理论和实验生物技术、计算机数学模型等方法整合研究动态生物系统网络。生物系统的结构理论和生物系统技术,研究基因组——生物体复杂系统与细胞分子网络系统的动态结构发生与进化,分析基因组的逻辑程序和人工设计原理。细胞信号传导、基因调控网络、代谢反应链和基因反馈调控的自组织化人工设计和基因、基因链、基因组人工合成等系统生物工程开发,可用于复杂疾病机理分析、药物分子筛选和转基因表达系统的生物反应器、纳米生物计算机等。

By application of systems methodology,experimental and computational technology,systems biology is disciplinary investigated in the field of biosystem networks.To study the biosystems of genome-organism complexity and Evo-Deve dynamic structures of cell molecular network systems,the structurity theory and technology of biosystems are discussed in the analysis of logic programs and re-design principles of genomes.Engineering of systems biology for the design and synthesis of evolutional artificial cell at the aspects of signal transduction pathways,gene regulatory network,metabolism bio-reaction chains and feedback regulation of genes self-organization,and used for genes analysis,drug discovery of complex diseases and construction of transgenic bioreactors etc.