呼吸机相关性肺炎32例临床分析

Clinical analysis of 32 cases with ventilator-associated pneumonia

目的:探讨呼吸机相关性肺炎(VAP)的临床特点,为有效防治VAP提供科学依据。方法:回顾性分析2007年1月～2010年12月我院收治的32例VAP患者的临床资料。结果:机械通气2～5 d的VAP发生率为20.45%,机械通气5 d以上的VAP发生率为57.50%,两者比较差异有统计学意义(P<0.05);VAP患者的病原菌以革兰阴性杆菌为主,占69.36%;多种致病菌感染者的死亡率高于单一致病菌感染患者,两者比较差异有高度统计学意义(P<0.01)。结论:呼吸机相关性肺炎的发生率高,治疗难度大。临床应以预防为主,尽量减少机械通气的时间,合理使用抗生素,以降低呼吸机相关性肺炎的发生。

Objective： To explore the clinical features of ventilator-associated pneumonia（VAP） in order to provide scientific evidence for effective prevention and treatment of the disease.Methods： The clinical data of 32 cases with VAP patients were analyzed retrospectively in our hospital from January 2007 to December 2010.Results： The incidence of VAP among patients who received 2-5 days of mechanical ventilation was 20.45%,and that of patients who received more than 5 days of mechanical ventilation was 57.50%,with significant difference between the two groups（P〈0.05）.69.36% of the pathogenic bacteria of VAP patients were G-coli.The mortality rate of patients with multiple kinds of pathogenic bacteria infection was higher than those with single kind of bacteria infection,the difference was significant（P〈0.01）.Conclusion： The incidence of VAP is relatively high and the disease is difficult to treat.Thus it’s important to prevent the disease by reducing mechanical ventilation time and by using antibiotics appropriately.