214例郁证医案用药规律数理分析

Mathematical Analysis of Medication Rule in Medical Records of Depression Syndrome:A Report of 214 Cases

目的:分析214例郁证医案中的用药规律,并探讨郁证的证治规律。方法:以214例古代郁证医案为研究对象,进行频数分析和关联规则分析。结果:涉及药物313种,使用频数最高的药物依次是茯苓、甘草、当归、香附,关联密切的药物组合方为茯苓、当归、白芍、甘草、人参、生姜、柴胡、大枣、白术、郁金、香附、陈皮。结论:用数理方法分析郁证医案的用药特点为疏肝健脾、理气活血,符合现行的中医学理论,能为临床提供参考。

Objective： To explore the medication rule in the ancient medical records of depression syndrome by mathematic analysis. Methods： Two hundreds and fourteen ancient medical cases of depression syndrome were studied by frequency analysis and association analysis. Results： In all of the analyzed medical records, 313 kinds of herbs were involved, and Poria, Radix Glycyrrhizae, Radix Angelicae Sinensis, and Rhizoma Cyperi had the highest usage frequency in turn. According to the results of association analysis, the prescription for depression syndrome should include Poria, Radix Angel icae Sinesis, Radix Paeoniae AIba, Radix Glycyrrhizae, Radix Ginseng, Rhizoma Zingiberis Recens, Radix Bupleuri, Fructus Jujubae, Rhizoma Atractylodis Macrocephalae, Radix Curcumae, Rhizoma Cyperi, Pericarpium Cirri Reticulatae. Conclusion： Medication rule for the depression syndrome in medical records shoed by mathematical analysis is characterized by invigorating spleen and smoothing liver, promoting flow of Qi and activating blood, which is in accordance with the present Chinese medical theory, and can provide a reference for clinic.