摘要
目的:比较半开放式静脉输液器2种排气方式对药液中不溶性微粒污染的影响情况。方法:模拟临床输液操作,分别采用上、下部排气方式对半开放式静脉输液器进行排气,同时对药液中不溶性微粒进行检测。结果:经检测,≥10μm的不溶性微粒,上、下部排气方式结果分别为(3.11±0.82)、(4.21±0.87)个/mL,t值为3.985,P=0.000;≥25μm的不溶性微粒,上、下部排气方式结果分别为(0.19±0.90)、(0.36±0.10)个/mL,t值为2.374,P=0.000。2种排气方式比较差异具有统计学意义(P<0.01)。结论:半开放式静脉输液器采用上部排气方式对减少药液不溶性微粒方面优于下部排气方式。
OBJECTIVE: To compare the insoluble particles of liquid medicine resulted from 2 kinds of exhaust methods of semi-open intravenous infusion apparatus. METHODS: In this research, up exhaust method and low exhaust method were separately used on semi-open intravenous infusion apparatus, and insoluble particles of liquid medicine were detected. RESULTS: The fig- ures for insoluble particles which were ≥10μm were (4.21 ± 0.87) particals/mL by low exhaust method and (3.11 ± 0.82) particals/ mL by up exhaust method (t=3.985, P=0.000). The figures for insoluble particles which were ≥25 μm were (0.36 ± 0.10) particals/mL by low exhaust method and (0.19 ± 0.90) particals/mL by up exhaust method (t=2.374, P=0.000). There was significant difference between them (P〈0.01). CONCLUSION: Up exhaust method is better than low exhaust method in reduction of insoluble particles in liquid medicine.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第37期3551-3552,共2页
China Pharmacy
关键词
半开放式静脉输液器
排气方式
不溶性微粒
Semi-open intravenous infusion apparatus
Exhaust methods
Insoluble particles