纳米羟基磷灰石仿生骨材料的研究进展

Research progresses in nano-hydroxyapatite biomimetic bone materials

纳米羟基磷灰石仿生骨材料因其与天然骨结构和成分相近，已成为组织工程领域研究的热点之一。介绍了纳米羟基磷灰石的各种制备方法及其复合材料的合成方法，并对纳米羟基磷灰石复合材料的特性进行了说明。通过将纳米羟基磷灰石表面修饰改性后，其复合材料有着广阔的应用前景，可用于修复骨缺损，也可以作为药物载体治疗肿瘤。对近年来纳米羟基磷灰石仿生骨材料的研究进展进行了综述。

Nano-hydroxyapatite biomimetic bone materials have become a hotspot in the field of tissue engineering research due to the similarity of the structure and composition to natural bone. This article describes a variety of preparation of nano-hydroxyapatite and synthesis of nano-hydroxyapatite composite, as well as the properties of nano-hydroxyapatite composite materials. Through surface-modification nano- hydroxyapatite composite materials will have a potential application foreground including bone defects repair, drug carrier for cancer treatment. In this paper, research progress of nano-hydroxyapatite biomimefic bone materials in recent years were reviewed.