我国慢性胰腺炎临床流行病学特征

Clinical features and epidemiologyof chronic pancreatitis in china

西方国家仅有少数中心对慢性胰腺炎(CP)的病因、临床特征和自然病程等进行了系统的报道。由于种族、地理、社会经济文化背景等差异,我国CP在发病、病因、临床表现等方面可能有着独特的流行病学特征。近几年国内进行了多中心联合的问卷调查研究并建立了数据库,目前在分析整理相关数据。总体来说,我国CP发病率呈上升趋势。饮酒和胆道疾病逐渐成为主要的病因。疼痛是CP的主要临床表现。内镜超声(EUS)和ERCP等内镜诊治方法行之有效,内镜治疗联合体外震波碎石疗效确切。

A paucity of reports on the etiology, clinical characteristics, natural course, and management of chronic pancreatitis （CP） are available from centers in western countries.With totally different ethnic and cultural background, as well as socioeconomic status, CP in China has shown special epidemiology characters, including pathogenesis, etiology and clinical characteristics. Recently, China has conducted a joint survey study based on multicenter, and established a database, which has made great progress. However, the incidence of CP is rising rapidly in China. Alcohol and biliary stones are becoming the main causes and disabl＇ing pain is usually the main symptom. Endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography are effective diagnostic methods with high sensitivity and specificity. Extracorporeal shock-wave lithotripsy with endoscopic clearance of stone fragments is equally effective. In comparison with western countries on the clinical features and epidemiology of CP, diagnosis and treatment suitable to the situation in China can be established.