慢性胰腺炎并发门静脉高压症的诊断与治疗

Diagnosis and treatment of chronic pancreatitis with portal hypertension

慢性胰腺炎并发门静脉高压症(PHT)的主要发病机制为脾静脉受压或血栓形成,造成脾静脉闭塞;通常同时表现慢性胰腺炎和PHT症状,慢性上腹痛及腰背部疼痛是慢性胰腺炎最常见症状,PHT的表现是不同程度的脾肿大和脾功能亢进,孤立的胃底静脉曲张、上消化道出血不多见。通过多普勒超声、CT、MRI以及血管成像多可得出明确诊断。治疗应既针对原发病又要针对门静脉高压症,强调个体化治疗。由慢性胰腺炎引起的PHT是可以治愈的。

It is the major pathogenesis of chronic pancreatitis with portal hypertension （PHT） that the splenic vein compression or thrombosis, resulting in splenic vein occlusion. It usually shows symptoms of both chronic pancreatitis and PHT. The most common symptoms of chronic pancreatitis is that chronic upper abdominal and lumbar back pain. The performance of PHT is the different degrees of splenomegaly and hypersplenism, and isolated gastric varices, but the upper gastrointestinal bleeding is rare. It can be diagnosed by Doppler ultrasound, CT, MRI and angiography. Treatment should be aimed at both the primary disease and PHT. The individual treatment should be emphasized. The chronic pancreatitis with PHT can be cured with good prognosis.