4Ilkova H,Glaser B,Tunckale A,et al.Induction of long-tem glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care,1997,20:1353-1356.
5Yki-Jarvinen H. Pathogenesis of non-insulin dependent diabetes mellitus. Lancet,1994,343:91-95.
6Elizabeth D,Robertson RP. Differentiation between glucose-induced desensitization of insulin secretion and beta-cell exhaustion in the HIT-T 15cell line. Diabetes,1998,47:606-611.
7Del Prato S,Marcherri P,Bonadonna RC. Phasic insulin release and metabolic regulation in type 2 diabetes. Diabetes,2002,51(Suppl 1):s109-116.
8Sivitz WI. Lipotoxicity and glucotoxicity in type 2 diabetes.Effects on development and progression. Postgrad Med,2001,109:55-59,63-64.
9Fenerici M Hemal M.Perego L,et al.Highglucose causes apoptosis in cultured human pancereatic islets of langerlums:a potemial role for regulation of specifio Bcl family genes toward an apptotic cell death program.Diabetes 2001;50(6):1290-1301.