110例婴幼儿轮状病毒肠炎心肌损害临床分析

Analysis of the relationship between the myocardial damage with the rotavirus enteritis in 110 cases of infants

目的:探讨轮状病毒肠炎患儿合并心肌损害的发生情况。方法:将110例粪便轮状病毒(RV)抗原阳性的肠炎患儿作为观察组,选择同期治疗的110例RV抗原阴性的肠炎患儿作对照组,比较两组患儿肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、谷草转氨酶(AST)及心电图异常发生情况。结果:观察组CK、CK-MB、LDH、AST等各项指标均显著高于对照组,差异有统计学意义(P<0.01);观察组患儿心电图异常发生率为47.27%(52/110),对照组患儿心电图异常发生率为21.82%(24/110),两组比较有显著统计学差异(P<0.01)。结论:轮状病毒肠炎患儿容易合并心肌酶谱及心电图并常,在治疗肠炎的同时需注意心肌的保护。

Objective：To explore the relationship of the myocardial damage with the rotavirus enteritis in infants.Methods：110 cases of infants with RV antigen-positive as the observation group and 110 cases of infants with RV antigen-negative enteritis as the control group were studied,all of the infants were phlebotomized to detect the serum levels of AST,CK,CK-MB,LDH,and also they were checked by electrocardiogram （ECG）.Results：The level of the CK,CK-MB,LDH,AST in the observation group were higher than that in the control group,there was a significant statistical difference between them（P0.01）;The rate of abnormal in ECG in the control group was 21.82%（24/110）,and that in the observation group was 47.27%（52/110%）,there was a significant statistical difference between them（P0.01）.Conclusion：RV enteritis in infants can cause the change of the level of myocardial enzymes and ECG,we should attach importance to the protection of the myocardium.