多次捐献机采血小板后献血者外周血象的变化

The changes of peripheral blood indexes in donors donating blood several times for apheresis platelet concentrates

目的研究多次捐献机采血小板后献血者外周血象的变化情况。方法选择20名自愿捐献机采血小板达10~38次的献血者(每次间隔期为1~2个月),在首次和末次采集血小板前分别进行外周血象的检测,进行统计分析。结果多次捐献机采血小板的献血者,末次采集前外周血小板数(PLT)与首次采集前PLT、正常值均数相比,差异均无统计学意义(P>0.05),外周血中的红细胞数(RBC)、白细胞数(WBC)、血红蛋白浓度(Hb)并未发生明显的变化,但血小板分布宽度(PDW)增加,血小板平均体积(MPV)、大形血小板比例(P-LCR)下降,且差异有统计学意义(P<0.01)。结论献血可以促进骨髓的造血功能,对机体并无明显不利的影响。

Objective To study the changes of peripheral blood several times indexes in donors donating blood for apheresis platelet concentrates. Methods 20 donors who donated blood for apheresis platelet concentrates 10-- 38 times （interval： 1 -- 2 months）, were enrolled and detected for peripheral blood indexes respectively before the first and the last time for donating platelet, and the results were analyzed. Results Of all enrolled donors,the platelet number, red blood cell number,white blood cell number and haemoglobin concentrates and the average value before the last donating blood were not statistical different with those before the first donating（P^0.05） ,but mean platelet volume and platelet large cell rate were decreased（P（0.01）. Conclusion Blood do nation could promote hematopoiesis of the bone marrow,and might not be harmful to the body health.