期刊文献+

抗血小板药物在糖尿病治疗中的临床应用 被引量:1

下载PDF
导出
摘要 糖尿病是危及人类健康的全球性疾病,其巨大危害在于导致各种严重的并发症。目前,糖尿病血栓性事件是影响患者生活质量和威胁患者生命的主要原因,其中血小板功能异常在动脉血栓形成过程中扮演着重要的角色。研究发现,糖尿病患者的血小板功能将发生多种改变,主要表现为:(1)膜流动性下降;(2)Ca2+、Mg2+代谢稳态发生变化(细胞内Ca2+流动增加,Mg2+减少);(3)花生四烯酸代谢增加;
作者 田杰 刘纯
出处 《临床合理用药杂志》 2011年第01X期128-130,共3页 Chinese Journal of Clinical Rational Drug Use
  • 相关文献

参考文献20

  • 1Steering Committee of the Physicians′Health Study Research Group.Final report on the aspirin component of the ongoing Physicians′Health study[J].N Engl J Med,1989,32l(3):129-135.
  • 2ETDRS investigators.Aspirin effects on mortality and morbidity in patients with diabetes mellitus.Early treatment diabetic retinopathy study report 14[J].JAMA,1992,268(10):1292-1300.
  • 3Hansson L,Zanchetti A,Carruthers SG,et al.Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension:principal results of the Hypertension Optimal Treatment (HOT) randomised tria1.HOT Study Group[J].Lancet,1998,351(9118):1755-l762.
  • 4Ridker PM,Cook NR,Lee IM,et al.A randomized trial of low-dose aspirin in the primary prevention of cardio-vascular disease in women[J].N Engl J Med,2005,352 (13):1293-1304.
  • 5Ogawa H,Nakayama M,Morimoto T,et al.Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes:a randomized controlled trial[J].JAMA,2008,300(18):2134-2141.
  • 6Raghavan RP,Laight DW,Shaw KM,et al.Aspirin and Diabetes[J].Br J Diabetes Vasc Dis,2006,6(2):74-82.
  • 7American Diabetes Association.Standards of medical care in diabetes-2008[J].Diabetes Care,2008,31 (Suppl 1):S12-S54.
  • 8Antithrombotic Trialists′Collaboration.Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death,myocardial infarction,and stroke in high risk patients[J].BMJ,2002,324(7329):71-86.
  • 9Bhatt DL,Marso SP,Hirsch AT,et al.Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus[J].Am J Cardiol,2002,90(6):625-628.
  • 10Diener HC,Ringleb PA,Savi P.Clopidogrel for the secondary prevention of stroke[J].Expert Opin Pharmacother,2005,6(5):755-764.

同被引文献9

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部