肥胖糖尿病病人注射胰岛素针皮下停留时间的研究

A Study On the Residence Time of Needles for Insulin Injection into Obese Diabetes Patients

目的:探讨肥胖糖尿病病人皮下注射胰岛素针停留时间。方法:根据每日皮下注射胰岛素剂量的不同分为30单位以下、30～40单位(不含40单位)和40～60单位三个组,每个组再分为传统方法(6 s)、9 s、11 s和13 s四个小组,分别计算注射80次后进行分析。结果:三个组均显示针停留时间在11 s和13 s时,针眼药液渗出现象明显减少(χ2>17.72,P<0.01),而仅在40～60单位组显示停留13 s与11 s比较有显著性差异(χ2=4.32,P<0.05),余未显示有差异性。结论:每日胰岛素用量<40单位时,针停留时间以11 s最为合适,≥40单位时,针停留时间以13 s效果最为可靠。

Objective：To study the optimal residence time insulin injection for obese diabetic patients.Method：According to daily insulin injection dose,the patients are divided into three groups： below 30 units,30~40 units（excluding 40 units） and 40~60 units.Each group is further divided into 4 subgroups.Different needle residence times,including 6 seconds（traditional method）,9 seconds,11 seconds or 13 seconds,were applied for each individual subgroups respectively.The results are collected and analyzed after 80 times of injection.Result：All the three groups have significantly（χ217.72,P0.01） reduced the liquid leakage at needle eye when the residence time is 11 seconds or 13 seconds.For most of the groups the residence time of 11 seconds and 13 seconds showed no significant difference except for the group of 40~60 units（χ2=4,32,P0.05）.Conclusion：The optimal residence time for those patients with daily injected dose less than 40 units is 11s while the optimal value changes to 13s for patients with daily injected dose more than 40 units.