摘要
1978年于西安市第二奶牛场,解剖36例患出血性胃肠炎与胃溃疡的病例中,发现5例皱胃毛霉菌病的典型病灶。这些病例中还伴有念珠菌感染与曲霉菌毒素中毒。病牛主要呈现顽固性、黑色粘液性腹泻,10余天后死亡。也有表现分娩衰弱,急性坏死性子宫内膜炎和化脓坏死性乳房炎等变化。患皱胃毛霉菌病的乳牛,显示三种类型的病理变化。即急性早期阶段,坏死病变以循环障碍为主;亚急性中期阶段,呈凝固性坏死与梗塞;慢性晚期阶段,病理变化与肉芽肿类似。乳牛毛霉菌病的病原为微小根毛霉、伞枝犁头霉和足样根霉。三种菌各以1～3千万个孢囊孢子耳静脉注射家兔,腹腔注射豚鼠。结果三种菌致家兔于1～4日内死亡,豚鼠于3～7日内死亡。作者认为,毛霉菌病的致病真菌在饲料及乳牛体严重侵染,是本病的直接病因,而过多饲喂精饲料造成瘤胃酸中毒和长期使用抗生素药物,是该场乳牛皱胃毛霉病的诱发因素。
Investigation on mucormycosis of five cows accompanied by moni-liasis and aspergillotoxicosis were carried out and the Mucorpusillus, Absidialichthemi , Rhizopus rbizopodiformis were isolated from their abomasums. These strains of mucor exhibited strong virulence to rabbits and guinea pigs. All rabbits ( 6/6 ) and guinea pigs (3/3) died in 1 to 7 days after the sporangiospore ( 10-30 million ) were administered intraveously and intraperitoneally respectively.
The study suggests that the contaminiated feedstufis and environment were assumed to be the direct cause of the disease, but excess of concentrated feed resulted in acidosis and the antibiotics always used were the indirect causes.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1990年第1期74-79,共6页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
关键词
乳牛
毛霉菌病
并发症
Milk cow, Mucormycosis, Mucorpusillus, Absidialichemi, Rhizopus rhizopodiformis
