摘要
采用传统的酸水浸提法与离子交换法相结合的工艺，从一叶萩中提取一叶萩碱，经过单因素试验与响应曲面法进行优化，最终确定最优的生产工艺参数为液料比为19：1，水浴温度为81℃，萃取次数为3次，乙醇浓度为89％，一叶萩碱的得率为0．47％，纯度为91．5％。从而有效优化了一叶萩碱的提取工艺。
Securinine was extracted from securinega suffruticosa using the traditional technology coordinated by acid water extraction process and ion exchange process. The optimal production process parameter was finally determined by single factor experiment and response surface method. The proportion of liquid material was 19：1, the bath temperature was 81℃, the extraction times was 3, and the ethanol concentration was 89% .Under above conditions, the extraction rate of securinine was 0.47%, and purity was 91.5%.
关键词
一叶萩碱
提取
优化
Securinine
Extraction
Optimization
