抑郁状态对冠状动脉介入术后冠心病患者预后的影响

Influence of depression on prognosis of patients with cornary heart disease after successful PCI surgery

目的探讨抑郁状态对冠状动脉粥样硬化性心脏病(冠心病)成功行经皮冠状动脉介入术(PCI)后患者预后的影响。方法选择2006～2009年本院住院冠心病并成功行PCI治疗的患者302例。按抑郁评定标准分为抑郁组(n=78),对照组(n=224)。1年后对两组预后进行评估。结果抑郁组患者血C反应蛋白、白细胞总数,再住院率,Holter监测发生房性、室性心律失常、窦性心动过速均较对照组高,自觉症状缓解率降低。结论抑郁状态明显影响PCI术后冠心病患者的预后。

Objective To discuss influence of depression on prognosis of percutaneous coronary intervention（PCI） patients with coronary heart disease after successful surgery.Methods 302 patients diagnosed with cornary heart disease and treated with PCI successfully were divided into two groups based on Hamilton Depression Rating Scale.The experimental group（group A,n=78） had depression;The control group（group B,n=224） without depression.The prognosis situations of the two groups were comparted one year after the surgery.Results Inflammatony index of CRP,leukocyte count,returned visit rate,Holter monitoring ventricular arrhythmia and sinus tachycardia of the experimental group were higher than the corresponding indexes of the control group.The remission rate was reduced.Conclusion Influence of depression on arrhythmia symptoms and subjective symptoms of PCI patients with coronary heart disease after surgery is significant.