血瘀量化评分与老年男性骨密度相关性分析

Analysis on the correlations between quantitative scores of blood stasis and bone mineral density in elderly males

目的:探讨血瘀量化评分与老年男性骨密度的相关性,为临床治疗老年男性骨质疏松症提供更好的中医理论参考及有效治疗法则。方法:选择109例年龄≥60岁的老年男性作为研究对象,测定其腰椎和股骨骨密度T值。取L2～L4骨密度的平均值作为腰椎总体骨密度;取左股骨颈、大转子及W ard’s区骨密度平均值作为股骨总体骨密度。同时对所有研究对象参照陈可冀血瘀证诊断标准中的项目进行检查,计算其血瘀评分。分别对患者的年龄、血瘀评分与骨密度进行直线相关分析。结果:腰椎骨密度与年龄、血瘀评分呈负相关(r=-0.327,P=0.001;r=-0.405,P=0.000),股骨骨密度与年龄、血瘀评分呈负相关(r=-0.601,P=0.000;r=-0.716,P=0.000)。结论:老年男性骨质疏松的发生与血瘀密切相关,随着血瘀程度加重,老年男性骨质疏松程度亦会加重。

Objective：To explore the correlations between quantitative scores of blood stasis and bone mineral density（BMD）in elderly males for the purpose of providing better TCM theoretical reference and effective therapeutic principles for the clinical treatment on osteoporosis in elderly males.Methods：One hundred and nine elderly males aged over 60 years were chosen as research objects,and BMD T-values of their lumbar vertebrae and femur were measured.The average BMD values in the L2-L4 regions were measured as overall BMD of lumbar vertebrae,and the average BMD values in the neck,greater trochanter and Ward＇s regions of left femur were measured as overall femoral BMD.Meanwhile,all the objects were inspected according to the items listed in the diagnostic criteria for blood stasis formulated by Chen keji at the aim of measuring their blood stasis scores.The ages,blood stasis scores and BMD of the objects were processed with the linear correlation analysis.Results：There was a negative correlation between BMD in lumbar vertebrae and,ages（r=-0.327,P=0.001）,and between BMD in lumbar vertebrae and blood stasis scores（r=-0.405,P=0.000）.There was a negative correlation between femoral BMD and ages（r=-0.601,P=0.000）,and between femoral BMD and blood stasis scores（r=-0.716,P=0.000）.Conclusion：There is a close relationship between the occurrence of osteoporosis in elderly males and the blood stasis.The degree of osteoporosis will increase accompanied with the increase of degree of blood stasis.