养血清脑颗粒治疗慢性脑供血不足90例疗效观察

Efficacy Observation of 90 Cases of Chronic Cerebral Circulation Insufficiency Treated with Yangxue Qingnao Capsules

目的观察养血清脑颗粒治疗慢性脑供血不足的临床疗效。方法将慢性脑供血不足患者90例随机分为治疗组和对照组。两组均按需给予降血压、降血糖、降脂及抗血小板药物常规治疗。治疗组在常规治疗基础上加服养血清脑颗粒,对照组加服曲克芦丁治疗。两组患者治疗前后均用TCD检查测量大脑前动脉、基底动脉和大脑中动脉血流量。治疗前后分别检查肝肾功能,并观察不良反应。结果治疗组临床疗效总有效率为86.7%,优于对照组的66.7%(P<0.05)。治疗组治疗后颈内动脉、基底动脉血流量较治疗前有明显提高(P<0.05),且与对照组治疗后比较差异也有统计学意义(P<0.05)。两组治疗后肝肾功能均未见明显改变,未发现明显副作用。结论养血清脑颗粒可以增加脑血流量,改善临床症状。

Objective To observe the clinical efficacy on chronic cerebral circulation insufficiency（CCCI）treated with yangxue qingnao capsules.Methods 90 cases of CCCI were divided randomly into a treatment group and a control group.The conventional treatment was given in either group,such as lowering blood pressure,blood glucose and lipid and antiplatelet.In treatment group,on the basis of conventional treatment,yangxue qingnao capsules were prescribed.In control group,troxerutin was supplemented.TCD was used to detect blood flow in anterior artery,basilar artery and middle artery of the cerebrum before and after treatment in two groups.The liver and kidney functions were tested before and after treatment separately.Additionally,the adverse reaction was observed.Results The total effective rate was 86.7% in treatment group,which was better than 66.7% in control group（P0.05）.In treatment group,after treatment,blood flow in posterior carotid artery and basilar artery was improved apparently as compared with that before treatment（P 0.05）.The comparison of it with control group presented significant difference（P0.05）.There was no apparent change in liver and kidney functions after treatment in either group.The apparent side effects were not discovered.Conclusion Yangxue qingnao capsules increase cerebral blood flow and improve in clinical symptoms.