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新型抗耐甲氧西林金葡菌抗生素研究进展 被引量:3

Progress in research of new anti-methicillin resistant Staphylococcus aureus antibiotics
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摘要 随着临床耐药病例日益增多,耐甲氧西林金葡菌(MRSA)已成为医院和社区获得性感染的主要元凶。MRSA蔓延趋势不断恶化,新型抗MRSA抗生素研究成为热点。本文综述新型抗MRSA抗生素特拉万星、头孢吡普与头孢洛林等新药的研究进展。 With the increase of drug resistance in clinic, methicillin resistant Staphylococcus" aureus (MRSA) has become the main culprits of hospital and community acquired infections. The spreading trend of MRSA becomes worse, and the research of new anti-MRSA antibiotics has been a hot focus of discussion. This review describes the progress in research of new anti-MRSA antibiotics such as telavancin, ceftobiprole and ceftaroline.
出处 《世界临床药物》 CAS 2011年第9期548-551,共4页 World Clinical Drug
关键词 耐甲氧西林金葡菌 特拉万星 头孢吡普 头孢洛林 methicillin resistant Staphylococcus aureus telavancin ceftobiprole ceftaroline
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参考文献21

  • 1Zhanel GG,Calic D,Schweizer F,et al.New lipoglycopeptides:a comparative review of dalbavancin,oritavancin and telavancin[J].Drugs,70(7):859-886.
  • 2Corey GR,Stryjewski ME,Weyenberg W,et al.Telavancin[J].Nature Reviews Drug Discovery,2009,8(12):929-930.
  • 3Lyseng-Williamson KA,Blick SKA.Telavancin[J].Drugs,2009,69(18):2607-2620.
  • 4Saravolatz LD,Stein GE,Johnson LB.Telavancin:a novel lipoglycopeptide[J].Clinical Infectious Diseases,2009,49(12):1908.
  • 5Murthy B,Schmitt-Hoffmann A.Pharmacokinetics and pharmacodynamics of ceftobiprole,an anti-MRSA cephalosporin with broad-spectrum activity[J].Clin Pharmacokinet,2008,47(1):21-33.
  • 6Hebeisen P,Heinze-Krauss I,Angehm P,et al.In vitro and in vivo properties of Ro 63-9141,a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci[J].Antimicrob Agents Chemother,2001,45(3):825-836.
  • 7Leonard SN,Cheung CM,Rybak MJ.Activities of ceftobiprole,linezolid,vancomycin,and daptomycin against community-associated and hospital-associated methicillinresistant Staphylococcus aureus[J].Antimicrob Agents Chemother,2008,52(8):2974-2976.
  • 8Fritsche TR,Sader HS,Jones RN.Antimicrobial activity of ceftobiprole,a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin,tested against contemporary pathogens:results from the SENTRY Antimicrobial Surveillance Program(2005-2006)[J].Diagn Microbiol Infect Dis,2008,61(1):86-95.
  • 9Noel GJ,Strauss RS,Amsler K,et al.Results of a doubleblind,randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by gram-positive bacteria[J].Antimicrob Agents Chemother,2008,52(1):37-44.
  • 10Noel GJ,Bush K,Bagchi P,et al.A randomized,double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections[J].Clin Infect Dis,2008,46(5):647-655.

同被引文献48

  • 1李忠海,钟海雁,郑锦星,袁烈江.槟榔提取物在小白鼠体内的抑菌作用[J].食品与机械,2007,23(5):81-83. 被引量:17
  • 2王一平,郭世民.中药抗菌作用研究思路[J].云南中医中药杂志,2007,28(6):5-7. 被引量:6
  • 3蔡芸,王睿.新型头孢菌素类抗生素ceftobiprole[J].中国新药杂志,2006,15(17):1504-1507. 被引量:4
  • 4尤启东.药物化学[M].北京:化学工业出版社,2004.178,409.
  • 5仲兆金.新的抗MRSA β-内酰胺类抗生素[J].国外医药(抗生素分册),2007,28(5):202-204. 被引量:4
  • 6Jones ME. In-vitro profile of a new β-lactam, ceftobiprole, with activity against methicillin resistant Staphylococcus aureus[J]. Clin Microbiol Infect, 2007,13(S2) : 17.
  • 7Adis Intemation Limited. Ceftobiprole Medocaril: BAL5788, JNJ30982081, JNJ30982081, RO65-5788, RO655788[J]. Drugs R D, 2006,7 (5) : 305.
  • 8Bush K, Heep M, Macielag MJ, et al. Anti-MRSAβ-lactams in development, with a focus on ceflobiprole: the first anti-MRSA fl-lactam to demonstrate clinical efficacy [J]. Expert Opin lnvestig Drugs, 2007,16 (4) : 419.
  • 9Lim D, Strynadka NC. Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureu[J]. Nat Struct Biol, 2002,9 ( 11 ) : 870.
  • 10Livermore DM. Can beta-lactams be re-engineered to beat MRSA[J]. Clin Microbiollnfect, 2006,12(2) : 11.

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