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乳腺癌保乳手术切缘评估技术与方法 被引量:1

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摘要 早期乳腺癌保乳手术(Breast—conservingtherapy,BCT)因能减轻患者心理负担,提供较好的美容效果,兼顾乳腺癌疗效和患者生活质量的优势,现已成为欧美国家治疗早期乳腺癌的首选术式。但BCT存在着较高的局部复发(10calrecur-reflce,LR)风险,一些临床试验报道局部复发率在6%~16%。大量研究均显示BCT的切缘状态与局部复发有关,BCT的阳性切缘率在20%~40%。如何正确地评估和处理原发灶手术切缘,是BCT实施过程中的一个非常关键的问题。
出处 《吉林医学》 CAS 2011年第26期5494-5496,共3页 Jilin Medical Journal
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  • 1Komoike Y,Akiyama F,Iino Y,et al.Ipsilateral breast tumor recurrence(IBTR)after breast-conserving treatment for early breast cancer:risk factors and impact on distant metastases[J].Cancer,2006,106(1):35.
  • 2Nottage MK,Kopciuk KA,Tzontcheva A,et al.Analysis of incidence and prognostic factors for ipsilateral breast tumor recurrence and its impact on disease-specific survival of women with node-negative breast cancer:a prospective cohort study[J].Breast Cancer Res,2006,8(1):R44.
  • 3Pleijhuis RG,Graafland M,de Vries J,et al.Obtaining adequate surgical margins in breast-conserving therapy for patients with early-stage breast cancer:current modalities and future directions[J].Ann Surg Oncol,2009,16(10):2717.
  • 4Jacobs L.Positive margins:the challenge continues for breast surgeons[J].Ann Surg Oncol,2008,15(7):1271.
  • 5Staradub VL,Hsieh YC,Clauson J,et aL Factors that influence surgical choices in women with breast carcinoma[J].Cancer,2002,95(6):1185.
  • 6Kunos C,Iatson L,Overmoyer B,et aL Breast conservation surgery achieving≥2 mm tumor-free margins results in decreased local-regional recurrence rates[J].Breast J,2006,12(1):28.
  • 7Vargas C,Kestin L,Go N,et al.Factors associated with local recurrence and cause-specific survival in patients with ductal carcinoma in situ of the breast treated with breast-conserving therapy or mastectomy[J].Int J Radiat Oncol Biol Phys,2005,63(8):1514.
  • 8Zavagno G,Goldin E,Mencarelli R,et al.Role of resection margins in patients treated with breast conservation surgery[J].Cancer,2008,112(10):1923.
  • 9Dillon MF,Hill AD,Quinn CM,et al.A pathologic assessment of adequate margin status in breast-conserving therapy[J].Ann Surg Oncol,2006,13(3):333.
  • 10Perou CM,Sorlie T,Eisen MB,et al.Molecular portraits of human breast tumors[J].Nature,2000,406(4):747.

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