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MMP-9和RECK在胃癌中的表达及意义 被引量:1

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摘要 目的:探讨胃癌患者基质金属蛋白酶-9(MMP-9)基因及RECK基因表达的情况.方法:采用免疫组织化学SP 法检测60例胃癌组织和20例正常胃粘膜组织中MMP-9和RECK的表达,并分析其表达与临床病理参数的关系.结果:胃癌组织中RECK表达降低,MMP-9表达明显升高,二者均与分化程度、浸润深度、有无淋巴结转移有显著相关性(P〈0.05);二者表达呈负相关(P〈0.05).结论:RECK与MMP-9在胃癌组织中的表达呈负相关,MMP-9及RECK基因在胃癌的进展中可能起重要作用.
出处 《医学信息(下旬刊)》 2011年第9期46-46,共1页 Medical information
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参考文献5

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二级参考文献5

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