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左旋门冬酰胺酶治疗儿童急性淋巴细胞白血病的不良反应及防治研究

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摘要 目的:探讨左旋门冬酰胺酶在治疗儿童急性淋巴细胞性白血病时不良反应及防治方法.方法:对15例确诊的急性淋巴细胞性白血病患儿45个化疗疗程的临床表现和不良反应进行观察分析.结果:12例患儿发生不良反应14例次,不良反应发生率为31.11%.主要的不良反应为凝血异常8.89%,肝功能异常6.67%,过敏反应11.11%和高血糖11.11%.诱导期和强化期副作用发生率无统计学差异.结论:应密切监测患儿各项临床检查,合理控制饮食,并及时诊断和处理化疗过程中的不良反应,提高患儿生存率.
作者 禹环
出处 《医学信息(下旬刊)》 2011年第9期150-150,共1页 Medical information
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参考文献6

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